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Updated: Jul 17, 2025

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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SARS-CoV和SARS-CoV-2主要蛋白酶及其抑制的结构和功能:综合性综述

Xin Li1, Yongcheng Song1

  • 1Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.

European journal of medicinal chemistry
|September 2, 2023
PubMed
概括

主蛋白酶 (Mpro) 对SARS-CoV和SARS-CoV-2复制至关重要. 这篇评论详细介绍了Mpro的细节.

关键词:
药物发现 药物发现主要蛋白质酶的主要蛋白质酶.这就是SARS-CoV-2病毒.小分子抑制剂小分子抑制剂

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