幸存下来的COVID-19危急病患者的长期结果:NUTRICOVID观察队列研究
J Álvarez-Hernández1, P Matía-Martín2, E Cáncer-Minchot3
1Hospital Universitario Príncipe de Asturias, Madrid, Spain.
Clinical nutrition (Edinburgh, Scotland)
|September 2, 2023
概括
COVID-19幸存者经历了严重的营养不良和功能障碍,在重症监护室 (ICU) 退院后. 然而,营养状况,身体功能和生活质量在接下来的一年里大大改善.
科学领域:
- 密集护理医学 密集护理医学
- 营养科学 营养科学
- 康复医学 康复医学 康复医学
背景情况:
- 重症监护室 (ICU) 退院后持续存在营养不良和肉症,影响康复,生活质量和发病率.
- 在ICU治疗后,对于2019年新冠病毒病 (COVID-19) 幸存者的长期营养和功能结果没有先前的证据.
- 这项研究调查了COVID-19幸存者在ICU后的营养状况,功能能力和与健康有关的生活质量 (HRQoL) 的一年进化.
研究的目的:
- 评估COVID-19幸存者在ICU出院后的长期营养和功能恢复.
- 为了评估12个月后ICU健康相关生活质量 (HRQoL) 的变化.
- 在这个患者群体中确定早期营养和功能支持策略的需要.
主要方法:
- 一个多中心的,野心的观察队列研究 (NUTRICOVID) 涉及16家医院.
- 包括COVID-19幸存者在第一个爆发期间被录入ICU.
- 收集关于体重,营养不良风险 (MUST),肉风险 (SARC-F),医疗营养治疗 (MNT),功能状态 (巴特尔指数) 和HRQoL (EQ-5D-5L) 在医院出院和出院后3,6和12个月的数据.
主要成果:
- 从医院出院到出院12个月后,体重,营养不良风险和肉症风险有显著改善.
- 功能依赖性显著下降,87.2%的患者在12个月后达到低依赖性或独立性.
- 与健康相关的生活质量 (HRQoL) 显著改善,EQ-VAS和平均健康值显著增加6个月,并保持稳定.
结论:
- 在ICU出院后,COVID-19幸存者表现出严重的营养和功能缺陷,以及低的HRQoL.
- 在出院后的12个月内,营养状况,功能能力和HRQoL的逐步改善是显而易见的.
- 发展和实施早期策略至关重要,以优化ICU后COVID-19患者的营养和功能恢复.
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