在芬兰赫尔辛基出生队列研究中,从出生到84岁的健康老龄化:一项纵向研究
Tuija M Mikkola1, Hannu Kautiainen2, Mikaela B von Bonsdorff3
1Public Health Research Program, Folkhälsan Research Center, Helsinki, Finland; Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
The lancet. Healthy longevity
|September 2, 2023
概括
健康衰老的关键指标健康生存概率在65岁时下降到50%以下. 整个生命的因素,从童年社会经济地位到中年营养,影响健康的衰老结果.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在人口层面上,健康老龄化的流行程度仍未确定.
- 这项研究通过检查健康生存概率来量化健康衰老的上限.
- 它还估计了临床评估健康衰老的患病率和决定因素.
研究的目的:
- 为了确定成年期健康生存的概率.
- 为了估计临床评估健康衰老的患病率.
- 确定影响健康生存和健康衰老的因素.
主要方法:
- 从1971年至2017年对赫尔辛基出生队列研究 (n=13,140) 的纵向分析.
- 使用国家注册,数据库和临床评估 (2001-04, 2017-18).
- 卡普兰-梅尔和考克斯生存回归;老化决定因素的后勤回归.
主要成果:
- 在65岁时,健康生存概率为42.8% (男性) 和40.1% (女性);在75岁时,为22.5% (男性) 和24.4% (女性).
- 儿童时期的社会经济地位,教育,母亲的BMI和早期的身高都影响了健康的生存.
- 只有19.6%的人符合所有六个健康衰老标准;中年营养和吸烟状态是关键决定因素.
结论:
- 在65岁时,健康生存概率下降到50%以下,这表明健康衰老有限.
- 生活过程因素显著影响健康生存和健康衰老.
- 推广健康的老龄化策略,必须采用一生历程的方法.
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