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在固体剂量形式的和桶排放中粉末流阻塞的风险应在活跃应激状态下预测制造

Karthik Salish1, Reto Maurer2, Chen Mao1

  • 1Small Molecule Pharmaceutical Sciences, Genentech, Inc., South San Francisco, CA 94080, United States.

Journal of pharmaceutical sciences
|September 2, 2023
PubMed
概括

准确预测粉末流阻塞需要测量主要的主应力 (σ1). 这项研究引入了一种新的模型,经过实验验证,以防止昂贵的制造问题,如形和拉索.

关键词:
活跃的压力状态 活跃的压力状态形形是指形的霍珀排放的排放方式被动压力状态被动压力状态.粉末的流量 粉末的流量拉托林是什么意思拉托林是什么意思拉托林是什么意思

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