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Updated: Jul 31, 2026

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
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Published on: June 17, 2016

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基质嵌套指导人体多能干细胞的囊形态发生,没有3D细胞外矩阵覆盖

Yun-Ping Chen1, Yue Shao1, Peng-Cheng Chen1

  • 1Institute of Biomechanics and Medical Engineering, Applied Mechanics Laboratory, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.

Acta biomaterialia
|September 2, 2023
PubMed
概括

人类多能干细胞 (hPSCs) 在软基质上自组织成3D囊,由基质嵌套和细胞力学指导,不需要3D细胞外基质 (ECM). 这揭示了新的组织形态发生机制.

关键词:
阿克托米奥辛的收缩性接触力学模型的模型细胞生成 (Cystogenesis) 是一个过程.弹性基板是一种弹性基板.人类多能干细胞是人类多能干细胞.

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A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells08:01

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