艾滋病毒患者的sarcopenic肥胖现象:对心血管预防和康复的影响
Jovana Milic1, Stefano Calza2, Samuele Cantergiani3
1Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
The Canadian journal of cardiology
|September 2, 2023
概括
在艾滋病毒感染者 (PWH) 中,sarcopenic肥胖 (SO) 现象型不同. 某些SO表型与亚临床心血管疾病 (CVD) 风险有关,突出了针对性预防策略的需要.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 肥胖症 (SO) 是越来越多的人生活与艾滋病毒 (PWH) 的关注.
- 了解SO表型及其心血管影响对于这一群体至关重要.
研究的目的:
- 确定PWH中SO表型的流行,发病率和风险因素.
- 调查SO表型与亚临床心血管疾病 (CVD) 之间的关联.
主要方法:
- 一项长度观察性研究,涉及2379名男性PWH.
- 被诊断为手握力较弱,尾骨肌指数 (ASMI) 较低,或身体性能电池 (SPPB) 较低而导致的肉类.
- 通过体重指数 (BMI) 或内脏脂肪组织 (VAT) 定义的肥胖;SO表型来自这些措施的组合. 亚临床心血管疾病通过动脉内心介质厚度 (IMT),动脉斑块和冠状动脉化 (CAC) 评分来评估.
主要成果:
- SO表型 (SO1-SO4) 的患病率在0.8%至20.8%之间.
- 发病率 (每100人/年) 不同,SO1为6.90和SO3为5.6.
- SO1与IMT≥1mm的风险增加有关,而SO3与较高的CAC分数 (>10) 相关.
结论:
- 在PWH中SO表型的发病率和流行率存在显著的变化.
- SO表型的存在对PWH的心血管风险评估和管理有影响.
- 针对性心血管预防和康复策略对于SO的PWH是有必要的.
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