相关实验视频

Updated: Jul 17, 2025

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

过期分娩与自闭症谱系障碍之间的关联:更新的系统性审查和元分析

Ensiyeh Jenabi¹, Sajjad Farashi¹, Amir Mohammad Salehi²

¹Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

European journal of medical research

|September 2, 2023

概括

过期分娩与儿童患自闭症谱系障碍 (ASD) 的风险更高有关. 这次元分析发现了一个显著的关联,在男性子组分析中解决了异质性.

科学领域:

围产期健康围产期健康
神经发育障碍神经发育障碍

背景情况:

调查过期分娩与自闭症谱系障碍 (ASD) 风险之间的关联.
解决过期分娩对公共卫生的相关性,后期分娩发生在5-10%的怀孕中.

研究的目的:

进行一项元分析,评估产后分娩与儿童自闭症谱系障碍 (ASD) 风险之间的关联.
综合来自多项研究的证据,以提供风险的综合估计.

主要方法:

对主要数据库 (PubMed,Scopus,Web of Science) 进行了系统的搜索,以确定相关的研究.
一个随机效应模型被用于元分析.
通过使用GRADE检查表来评估研究质量.

主要成果:

分析包括了18个记录,其中包括来自12个国家的1,412,667名儿童的数据.
在产后分娩和ASD风险之间发现了显著的关联 (RR=1.34,95% CI 1.10-1.58;OR=1.47,95% CI 1.03-1.91).
基于OR估计的初始异质性很高 (I2=94.1%),但基于RR估计的初始异质性不存在 (I2=6.6%). 按性别分类的子组分析解决了男性的异质性.

结论:

过期分娩代表了自闭症谱系障碍的高风险因素.
这种关联是显著的,尽管最初的异质性需要仔细解释.
性别特异性分析澄清了这种关系,特别是对于男性来说.

关键词:

自闭症谱系障碍自闭症谱系障碍分析研究研究的研究.在期后的产后.

更多相关视频

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

相关概念视频

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Modeling in Therapy

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...

Regression Toward the Mean

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...

Pathophysiology of Diabetes

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...