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Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
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使用寡合胆酸的仿制GLP-1A的设计,以利用载体介导内细胞形成,用于口服输送

Seho Kweon1,2, Jun-Hyuck Lee3, Seong-Bin Yang3

  • 1Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.

Biomaterials research
|September 2, 2023
PubMed
概括

研究人员通过将其与脱氧醇酸 (DOCA) 寡合体结合,开发出一种新的仿制葡萄糖类-1激动剂 (GLP-1A). 这种增强的GLP-1A表现出改善的口服生物可用性和强大的低血糖作用,为糖尿病治疗提供了一个有前途的新策略.

关键词:
通过ASBT介导的内细胞分裂.化学化学的酸.在的分子对接中,分子对接.寡头胆汁酸的胆汁酸.口服GLP-1激动剂的使用

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