型原生体在植物植物界中保留了抗生素耐药的机会性人类病原体
Chenshuo Lin1,2, Li-Juan Li1,2, Kexin Ren1
1Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen, 361021, China.
ISME communications
|September 2, 2023
概括
绿叶食品安全受到抗生素耐药机会性人类病原体 (OHPs) 的原生虫威胁. 这些原生动物,特别是Colpoda,可以内化和传播OHP,对公共卫生和食品安全构成风险.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 公共卫生 公共卫生
背景情况:
- 绿叶蔬菜可能含有机会性人类病原体 (OHP),构成食品安全风险.
- 原生体是植物圈微生物群落的关键组成部分,但它们在病原体传播中的作用尚不清楚.
研究的目的:
- 为了研究原生群体,人类病原体标记基因 (HPMGs) 和绿叶植物中的内共生生物.
- 了解植物圈中原始体和OHP之间的关联及其对公共卫生的影响.
主要方法:
- 从中国门超市抽取四种绿叶物种的样本.
- 使用全基因组测序对植物界原生体,HPMGs和原生体内共生体进行分析.
- 识别主要的病原体,如金黄色葡萄球菌和肺炎菌.
主要成果:
- 植物界原生和HPMG分布因叶绿色物种而异,其中中国鱼表现出最高的多样性和丰富性.
- HPMG的丰富性与形原生体的多样性和丰富性正相关.
- 孤立的原生体内含有抗生素耐药性,毒性因子和潜在的水平基因转移 (HGT) 的OHP.
- 科尔波达被确定为与OHPs相关的关键原生体,携带具有抗性和毒性基因的内共生体.
结论:
- 植物界原生体通过内化促进了耐药OHP的传播,影响了叶绿色食品的安全性.
- 了解原体-OHP相互作用对于食品安全监督和保护人类健康至关重要.
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