非质量乳腺病变的动力定量特征与对比增强超声波:一个前性研究
Ying-Yu Cai1, Yi-Chao Du2, Lei Zhao1
1Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The British journal of radiology
|September 3, 2023
概括
与对比度增强的超声波 (CEUS) 量化表征非质量乳腺病变 (NMLs). CEUS分析提高了诊断准确度,显示恶性NML具有超增强和快速洗入/洗出特征.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 非质量乳腺病变 (NMLs) 需要准确的特征来诊断.
- 传统的超声波和乳房扫描在充分评估NML时存在局限性.
- 与对比度增强的超声波 (CEUS) 提供了对病变血管性的定量评估.
研究的目的:
- 使用CEUS来定量表征NML.
- 评估CEUS与BI-RADS类别相关的诊断附加值.
- 评估CEUS在区分良性和恶性NML中的表现.
主要方法:
- 对接受灰度超声波和CEUS的NML患者进行前性研究.
- 对所有病变进行病理诊断.
- 放射科医生使用BI-RADS类别评估病变,然后在进行定量CEUS分析后重新评估.
- 对诊断性能的敏感性,特异性,PPV,NPV和AUC的计算.
主要成果:
- 分析了30种良性和24种恶性NML.
- 平均对比信号强度 (AI),冲洗速率 (WiR) 和在40s (I40) 的增强是关键的动力参数.
- 综合CEUS定量分析改善了诊断准确度 (AUC=0.904),具有95.8%的灵敏度和70.0%的特异性.
结论:
- 恶性NML在CEUS上表现出超增强和快速洗入/洗出模式.
- 对CEUS的动态分析反映了恶性NML的高血管性质.
- 与常规超声波相结合的CEUS可以提高恶性NML的诊断性能.
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