通过具有基表面工程的三维共价有机框架有效地捕获和高度敏感地分析okadaic酸
1College of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China; Engineering Technology Research Center on Reagent and Instrument for Rapid Detection of Product Quality and Food Safety in Fujian Province, Fuzhou University, Fuzhou 350108, People's Republic of China.
Journal of chromatography. A
|September 3, 2023
概括
开发了一种新的3D共价有机框架 ([OH]25-BD-TFPM) 与可调节的基团,用于高性能捕获酸 (OA) 海洋毒素. 这种功能性材料可以通过改进的痕迹分析能力,对贝类中的OA进行敏感检测.
科学领域:
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
- 环境科学 环境科学
背景情况:
- 海洋毒素,如酸 (OA),对人类健康构成重大风险.
- 在海鲜中有效检测OA的方法对于食品安全至关重要.
- 联有机框架 (COFs) 显示出由于其可调节结构的毒素吸附的希望.
研究的目的:
- 开发一种具有基基组的新型3D-COF,用于增强OA捕获.
- 为多模式相互作用 (疏水性和疏水性) 设计毛孔表面.
- 建立一种敏感的分析方法,用于在贝类中检测OA.
主要方法:
- 通过调整构建块比率来合成功能多元件COF ([OH]x-BD-TFPM).
- 使用SEM,XRD,FT-IR和BET.合成的COF的表征.
- 优化分散固相提取 (d-SPE) 与LC-MS/MS相结合用于OA分析.
主要成果:
- [OH]25-BD-TFPM COF在OA捕获方面表现出很高的性能.
- 优化的d-SPE方法实现了贝类中OA的低检测极限 (0.005μg/kg).
- 在强化和贝样本中,OA的恢复率高 (93.9110.2%).
结论:
- 基团表面工程是开发功能性3D-COFs的有效策略.
- 开发的[OH]25-BD-TFPM COF为微量OA检测提供了一个卓越的平台.
- 这种方法显著改善了现有的SPE材料用于海洋毒素分析.
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