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在OPTIVUS-复杂PCI研究多血管队列中的SYNTAX评分和1年结果

Masaomi Gohbara¹, Kiyoshi Hibi¹, Takeshi Morimoto²

¹Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.

The American journal of cardiology

|September 3, 2023

概括

最佳血管内超声波 (IVUS) 引导的皮肤冠状动脉干预 (PCI) 在中级SYNTAX评分 (SS) 患者的结果与低SS患者相比显示出类似的结果. 在IVUS引导的PCI后,高SS患者经历的重大心脏和脑血管不良事件 (MACCE) 显著增加.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
医疗器械医疗器械

背景情况:

对于具有中间SYNTAX分数 (SS) 的多血管疾病,最佳的再血管化策略仍然不清楚.
血管内超声 (IVUS) 引导的皮肤冠状动脉干预 (PCI) 是复杂冠状动脉疾病的关键技术.

研究的目的:

评估IVUS导向PCI在SS分层的多血管疾病患者的临床结果.
为了在不同SS组中比较主要的不良心脏和脑血管事件 (MACCE).

主要方法:

对OPTIVUS-Complex PCI研究多管队列的子研究.
1005名患者被分为低 (≤22),中等 (23-32) 和高 (≥33) 的SS组.
主要终点:一年的MACCE (死亡,心肌梗塞,中风或再血管).

主要成果:

与中级 (10.9%) 和低SS (9.5%) 组相比,高SS组的1年MACCE (25.0%) 显著更高 (p=0.003).
冠状动脉再血管是高SS患者MACCE增加的主要驱动因素.
多变量分析证实高SS与低SS (HR 3.19) 的MACCE风险显著更高,但中等与低SS (HR 1.20) 的风险不高.

结论:

在IVUS引导的多血管PCI中,中级SS患者的1年MACCE风险与低SS患者的风险相似.
与低SS患者相比,高SS患者在IVUS引导的多血管PCI后表现出更高的1年MACCE风险.

关键词:

在SYNTAX中,分数是SYNTAX的分数.药物释放的支架可以释放药物.静脉内超声波检查静脉内超声波检查通过皮肤进行冠状动脉干预.

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