在免疫媒介性炎症性疾病中对应急症状和工作障碍进行纵向研究
Murray W Enns1, Charles N Bernstein2, Lesley Graff3
1Department of Psychiatry, Max Rady College of Medicine, University of Manitoba, Canada.
Journal of psychosomatic research
|September 3, 2023
概括
痛苦症状如疼痛,疲劳,抑郁和焦虑显著增加了免疫介导疾病和精神疾病患者的工作障碍. 管理这些症状可以改善工作成果.
科学领域:
- 临床医学 临床医学
- 精神病学是一个精神病学.
- 类风湿病学 类风湿病学
背景情况:
- 工作障碍是慢性病患者的一个重要问题.
- 痛苦症状如疼痛,疲劳,抑郁和焦虑在各种患者群体中很常见.
- 了解这些症状与工作障碍之间的关系对于有效管理至关重要.
研究的目的:
- 研究应急症状 (疼痛,疲劳,抑郁,焦虑) 与工作障碍之间的关联.
- 在四个不同的患者群体中检查这种关联:多发性硬化症,类风湿性关节炎,炎症性肠道疾病和精神疾病.
主要方法:
- 纵向研究设计,在三年内进行四次数据收集.
- 用单变量和多变量量子逻辑回归分析来评估痛苦症状和工作障碍之间的关系.
- 模型考虑了痛苦症状的平均和变化得分,控制了社会人口统计学因素,并发症,身体残疾和认知功能.
主要成果:
- 疼痛,疲劳,抑郁和焦虑的严重程度显着与所有患者群体的更大工作损伤有关.
- 在单变量和多变量分析中,这些关联仍然显著.
- 具体发现包括疼痛 (0.27),疲劳 (0.21),抑郁 (0.35) 和焦虑 (0.24) 的平均贝塔系数在50百分点的工作障碍.
结论:
- 疼痛,疲劳,抑郁和焦虑是免疫介导疾病和精神疾病患者工作障碍的关键决定因素.
- 这些痛苦症状的有效临床管理有可能改善与工作相关的结果.
- 这凸显了对患者护理的整体方法的重要性,该方法应对疾病特异性和心理因素.
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