免疫检查点抑制剂后的急性肝衰竭
Thomas Renault1, Lucy Meunier2, Clément Monet3
1Department of Anesthesia and Intensive Care unit, Regional University Hospital of Montpellier, St-Eloi Hospital, University of Montpellier, Montpellier, CEDEX 5, France.
Clinics and research in hepatology and gastroenterology
|September 3, 2023
概括
免疫检查点抑制剂 (如阿特佐利祖马布和蒂拉戈卢马布) 造成的严重肝损伤可能危及生命. 血交换为这种严重的免疫媒介性肝炎提供了一种潜在的拯救生命的治疗方法.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 针对PD-L1和TIGIT的免疫检查点抑制剂 (ICI) 在癌症治疗中使用.
- 免疫媒介性肝炎是ICI已知的不良影响之一.
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