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中国城市炎症性肠病的发病率:全国基于人口的研究
Lu Xu1, Bingjie He2, Yexiang Sun3
1Research Center of Clinical Epidemiology, Peking University Third Hospital, Haidian District, Beijing, China; Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Haidian District, Beijing, China.
这项研究估计了中国城市的炎症性肠病 (IBD) 发病率,发现UC和CD的发病率在男性中更高. 城市化可能会增加未来IBD负担.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 关于中国炎症性肠病 (IBD) 负担的数据有限.
- 囊括性结肠炎 (UC) 和克罗恩病 (CD) 的IBD构成了日益严重的全球健康挑战.
研究的目的:
- 估计包括UC和CD在内的IBD在中国城市的发病率.
- 描述IBD在中国城市人口中的人口分布.
主要方法:
- 利用国家城市基本医疗保险数据 (2012-2016) 来计算IBD发病率.
- 采用了4年的洗期,并通过州区电子健康记录验证了发现.
主要成果:
- 确定了95,555名IBD患者;2016年的发病率为10万人/年10.04.
- 冠状病毒发病率明显超过了冠状病毒发病率 (12.61:1比).
- 发病率因年龄和性别而异,男性的发病率较高,UC和CD的与年龄相关的模式明显.
结论:
- 这是中国城市IBD分布的首个综合性肖像.
- IBD发病率表明与工业化和城市化有联系.
- 中国正在进行的城市化可能会导致IBD的未来负担增加.
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