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Updated: Jul 17, 2025

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对细菌UDP-糖2-表皮酶的结构分析揭示了催化前后活性位点的结构

James B Thoden1, James O McKnight1, Charles W Kroft1

  • 1Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, USA.

The Journal of biological chemistry
|September 3, 2023
PubMed
概括

这项研究特征了一种来自热友Thermus thermophilus的新型2-epimerase,揭示了其独特的基质结合和通过UDP-N-乙-d-葡萄糖胺 (UDP-GlcNAc) 的全调节. 这为极端环境中糖生物合成途径提供了新的见解.

关键词:
2,3-二甲胺-2,3-二氧化-d-曼努龙酸的二,3-二甲胺-2,3-二氧化-d-曼努龙酸.这是一种O-抗原.细菌 细菌 细菌是一种细菌.碳水化合物是一种碳水化合物.结晶学 结晶学是指结晶学.酶结构 酶结构脂多糖类糖化物 (Lipopolysaccharide) 是一种脂多糖类糖.

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