CANVAS,RFC1 DNA/RNA

Mohammad Hossein Abdi1, Bita Zamiri1, Gholamreza Pazuki1

  • 1Department of Chemical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.

PubMed
概括

致病重复扩张在RFC1导致CANVAS通过形成不寻常的G-四重复和三链核酸结构. 这些结构与非致病性重复不同,可能会驱动有毒DNA和有毒RNA的致病性.

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