相关实验视频

Updated: Jul 17, 2025

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
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Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 25, 2011

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通过β-冠状病毒非结构蛋白1对核糖体结合和宿主翻译抑制的进化保存策略

Stephanie F Maurina1, John P O'Sullivan1, Geetika Sharma1

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Journal of molecular biology
|September 3, 2023
PubMed
概括

来自SARS-CoV-2和其他β冠状病毒 (β-CoV) 的非结构性蛋白1 (Nsp1) 抑制宿主基因表达. 只有β-CoV Nsp1通过核糖体结合抑制翻译,提供潜在的治疗点.

关键词:
结构 RNA 结构 RNA 结构这就是SARS-CoV-2病毒.主机关闭 的主机关闭宿主-病毒相互作用翻译法规 翻译法规

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