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Updated: Jul 17, 2025

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双胞胎和单胞胎的长度儿童生长模式在州北部的KIDS队列中
Jessica L Gleason1, Edwina H Yeung1, Rajeshwari Sundaram2
1Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
The Journal of pediatrics
|September 3, 2023
概括
双胞胎的生长模式在7-9岁时显示赶上,没有增加超重或肥胖的风险. 这表明健康的发育,不像单身婴儿出生小的妊娠年龄 (SGA).
科学领域:
- 儿科内分泌学 儿科内分泌学
- 双胞胎研究 双胞胎研究
- 增长和发展 增长和发展
背景情况:
- 儿童成长模式对于长期健康至关重要.
- 对于孕期年龄 (SGA) 出生的婴儿可能会面临未来的心脏代谢风险.
- 了解双胞胎生长对于区分正常发育与潜在的健康问题至关重要.
研究的目的:
- 为了比较双胞胎与单身儿童的童年成长轨迹.
- 为了确定双胞胎是否表现出与SGA单生子相似的过度生长迹象.
- 评估双胞胎生长模式中的心脏代谢风险因素.
主要方法:
- 用上州KIDS队列 (2008-2010) 来获取婴儿数据.
- 比较身高,体重和BMIz分数在0-3岁和7-9岁.
- 分析了快速体重增加 (RWG) 和超重/肥胖风险在适合孕期年龄 (AGA) 双胞胎,AGA单生子和两个SGA双胞胎组.
主要成果:
- 在两个时间点上,SGA双胞胎组的体重和BMIz分数比AGA双胞胎低.
- 在7-9岁时,SGA双胞胎的身高与AGA双胞胎的身高相似.
- 双胞胎在婴儿期呈现较高的RWG,但后来没有增加超重/肥胖风险.
结论:
- 双胞胎在婴儿期经历了增长减弱的z-scores,但在学龄时正常化.
- 在任何双胞胎组中都没有观察到病态生长或增加超重/肥胖风险.
- 双胞胎的生长模式不同于SGA单胞胎,表明健康的追赶发展.
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