副心脏脂肪组织,全身炎症疾病和亚临床动脉动脉病之间的关系:系统性审查
Walter Masson1, Augusto Lavalle-Cobo2, Leandro Barbagelata3
1Council of Epidemiology and Cardiovascular Prevention, Argentine Society of Cardiology, Azcuenaga 980, Buenos Aires, Argentina; Cardiology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Reumatologia clinica
|September 3, 2023
概括
系统性炎症性疾病增加心上脂肪组织 (EAT),这是心血管风险的关键因素. 这种EAT与受影响患者的亚临床动脉样硬化密切相关.
科学领域:
- 心血管医学 心血管医学
- 炎症研究 炎症研究
- 医疗成像医学成像
背景情况:
- 系统性炎症性疾病 (SID) 可能通过表心脂肪组织 (EAT) 促进不良心血管影响.
- EAT的积累与心血管疾病的发病有关.
- SIDs,EAT和动脉样硬化之间的关系需要进行定量评估.
研究的目的:
- 在有系统性炎症疾病的患者中量化比较EAT与对照.
- 分析这些患者的EAT和亚临床动脉样硬化之间的关联.
主要方法:
- 按照PRISMA指南进行系统审查.
- 包括21项研究,包括1448名患者.
- 对EAT体积,厚度和面积进行定量分析.
主要成果:
- 与对照组相比,患有全身炎症疾病的患者表现出明显更高的EAT体积和厚度.
- 观察到 EAT 面积的增加在统计学上是不显著的.
- 大多数研究报告说,EAT和亚临床动脉动脉症之间存在显著的关联.
结论:
- 在患有全身性炎症疾病的患者中,心膜脂肪组织的增加.
- 增加的EAT在这个人群中与亚临床动脉样硬化有很强的关联.
- 需要进行前性研究来确定因果关系.
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