在神经临界护理中的急性损伤
Faeq Husain-Syed1,2, Tomonori Takeuchi3,4, Javier A Neyra3
1Division of Nephrology, University of Virginia School of Medicine, 1300 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
Critical care (London, England)
|September 3, 2023
概括
急性损伤 (AKI) 会使急性脑损伤 (ABI) 复杂化,使患者的结果恶化. 早期识别和针对性地管理AKI对于改善重症患者神经恢复至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 神经学 神经学
- 关键护理医学 关键护理医学
背景情况:
- 急性损伤 (AKI) 影响大约20%的急性脑损伤 (ABI) 患者.
- AKI会加剧神经损伤,通过代谢和炎症变化延长脑损伤和.
- 有效管理ABI需要识别和解决并发的AKI.
研究的目的:
- 审查神经系统疾病的重症成年人中AKI的发生和影响.
- 概述将AKI和ABI进展联系在一起的潜在机制.
- 在ABI.BI的背景下强调管理AKI的原则.
主要方法:
- 对ABI患者AKI的当前文献的综述.
- 讨论AKI和ABI之间的病理生理联系.
- 在ABI中对AKI进行量身定制的管理和预防策略的概述.
主要成果:
- 在ABI患者中,AKI显著恶化了结果.
- 具体的管理策略包括优化血压,内压,药物和液体的管理.
- 预防措施包括避免毒素和保持血液动力学稳定性.
结论:
- 在ABI患者中,AKI的管理需要量身定制的方法,包括流体和血液动力学优化.
- 在ABI患者中,替代疗法 (RRT) 需要仔细考虑RRT模式和潜在的神经并发症.
- 连续RRT通常是血动力学稳定性的首选,未来的研究应该专注于优化RRT和在ABI中利用AKI的生物标志物.
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