在智利的一个半农村社区中,主观记忆投诉的患病率和相关因素
Ximena Oyarzún-González1,2, Erin L Abner3,4,5, Pablo Toro2,6
1Dr. Donneyong's Laboratory, Division of Outcomes and Translational Sciences, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
主观记忆症 (SMC) 影响16%的成年人,女性和伴随疾病患者的患病率更高. 影响SMC的因素因年龄和认知状态而异.
科学领域:
- 神经科学是一个神经科学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 主观记忆问题 (SMC) 是痴呆症和阿尔茨海默病的潜在早期指标.
- 在年轻成年人中对SMC的研究,特别是在南美洲,是有限的.
- 毛尔队列研究 (MAUCO) 通过检查SMC流行率和相关因素来解决这一差距.
研究的目的:
- 为了确定MAUCO研究群体中SMC的流行率.
- 确定与SMC相关的人口,健康和认知因素.
- 探索年龄和认知状态作为SMC风险的潜在调节者.
主要方法:
- 从6,687名MAUCO参与者的基线数据进行横截面分析.
- 按年龄组 (38-59岁和60-74岁) 和认知状态分层 (使用迷你精神状态检查得分).
- 多项逻辑回归模型用于评估报告SMC (Yes,Sometimes,No) 的风险因素.
主要成果:
- 总体上,SMC患病率为16.4%,年轻 (15.9%) 和年长 (17.6%) 参与者之间略有差异.
- 女性性别,并发性病的存在和自我报告的健康状况不佳与SMC的几率增加有关.
- 与SMC相关的因素根据年龄和全球认知表现不同.
结论:
- 在成年年龄组中,SMC的患病率是显著的,受性别,健康状况和并发症的影响.
- SMC及其相关因素之间的关系是复杂的,并因年龄和认知功能而受到调节.
- 未来的研究应该考虑性别特异性分析,自我报告健康的作用,以及与流行病相关的SMC影响.
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