在局部发达的口腔状细胞癌的治疗和结果
Rathindra N Bera1, Sapna Tandon2, Akhilesh K Singh3
1Department of Oral and Maxillofacial Surgery, Dental Institute Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
National journal of maxillofacial surgery
|September 4, 2023
概括
对于局部发达的口腔状细胞癌 (OSCC),多式管理是关键. 切除的瘤最好进行手术,而同时进行的化疗和放射治疗可以为无法切除的病例提供生存益处.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 癌症治疗方法 癌症治疗方法
背景情况:
- 局部发达的口腔状细胞癌 (OSCC) 提出了复杂的管理挑战.
- 没有任何一种单一的治疗方法已经证明了最终的疗效.
- 治疗策略正在发展,对可操作疾病的外科手术越来越重视.
研究的目的:
- 对局部先进的OSCC进行审查和评估当前的治疗选择.
- 根据瘤切除能力对治疗方法进行分类.
- 为管理策略提供基于证据的概述.
主要方法:
- 对局部先进的OSCC治疗方法的综合文献综述.
- 疾病的分类:可切除,不可切除和技术上不可切除.
- 对各种治疗组合的治疗结果的分析.
主要成果:
- 手术是可切除局部先进的OSCC的主要治疗方法.
- 同时的化疗和放射治疗改善了无法切除疾病的存活率,而不是仅仅是放射治疗.
- 诱导疗法可以降低瘤的发展阶段,在技术上无法切除的病例中潜在地改善切除能力,但并不普遍推.
结论:
- 多模式治疗,手术作为可切除OSCC的基石,是必不可少的.
- 同时化学放射治疗是不可切除疾病的首选方式.
- 目前,针对性和免疫疗法仅用于复发性或转移性病例,而不是初始治疗.
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