双特异性蛋白酸酶6 (DUSP6) 的过度表达降低了粉样蛋白负载,并改善了5xFAD雄性小鼠的记忆缺陷

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Allen L Pan, Mickael Audrain, Emmy Sakakibara

    bioRxiv : the preprint server for biology
    |September 4, 2023
    PubMed
    概括

    双特异性蛋白合酶6 (DUSP6) 的过度表达改善了5xFAD雄性小鼠的记忆力和减少了粉样蛋白斑块. DUSP6还减少了两性人的神经炎症,突出了它对阿尔茨海默病的治疗潜力.

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