儿童门诊诊所和抗生素的使用归因于高价值的肺炎球菌合疫苗血清型
Laura M King1, Kristin L Andrejko2, Sarah Kabbani3
1School of Public Health, University of California, Berkeley, Berkeley, CA.
medRxiv : the preprint server for health sciences
|September 4, 2023
概括
新的肺炎球菌联合疫苗 (PCV15,PCV20) 针对额外的血清型,导致大量的儿科门诊诊所和抗生素处方. 额外的PCV20血清型代表着相当大的负担,这表明这些疫苗可能会减少急性呼吸道感染和儿童的抗生素使用.
科学领域:
- 儿童传染病 儿童传染病
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 肺炎链球菌会导致许多儿童急性呼吸道感染 (ARI),导致门诊诊和抗生素处方.
- 最近对15和20肺炎球菌合疫苗 (PCV15,PCV20) 的建议需要了解其额外血清型的影响.
结论:
- 在PCV15和PCV20中,额外的血清型对儿科门诊医疗保健的利用作出了重大贡献.
- 与PCV20额外血清型相比,PCV20额外血清型的访问和抗生素处方负担是PCV15额外血清型的五倍以上.
- 广泛采用高价值肺炎球菌合疫苗,特别是PCV20,有可能大幅减少儿童的ARI和相关抗生素使用.
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