脑活动的寿命轨迹与认知控制有关
Zhenghan Li1,2,3,4, Isaac T Petersen5, Lingxiao Wang6,7,3
1Institute of Brain Science and Department of Physiology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
bioRxiv : the preprint server for biology
|September 4, 2023
概括
认知控制大脑激活在整个生命周期中遵循一个反转的U形,在成年时达到顶峰. 与中年成人相比,年轻人和老年人表现出较弱的活化和更多的左脑主导地位.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 发展心理学 发展心理学
背景情况:
- 认知控制对于目标导向的行为至关重要.
- 以前的研究表明,用于行为和解剖学的认知控制的反转U形轨迹.
- 对于对认知控制的功能性大脑激活的与年龄相关的变化,人们的理解有限.
研究的目的:
- 为了研究在认知控制期间功能性大脑激活的寿命轨迹.
- 识别支持认知控制的大脑网络中的特定年龄模式.
- 为了比较不同年龄组的大脑激活模式.
主要方法:
- 进行了129项神经成像研究的综合元分析.
- 包括使用冲突任务的研究.
- 分析了3388名年龄在5岁至85岁之间的参与者的数据.
主要成果:
- 倒置的U形轨迹是认知控制相关的大脑激活的主要模式.
- 面对面对照控制网络显示了反转的U形轨迹,在24-40岁之间达到顶峰.
- 背部注意网络没有表现出明确的寿命轨迹.
- 无论是年轻人还是老年人,都表现出比中年人脑部活化较弱,左侧侧较大.
结论:
- 认知控制大脑激活表现出异质的寿命轨迹.
- 特定的大脑网络,如前端对象控制网络,遵循与年龄相关的不同模式.
- 年龄影响了与认知控制相关的功能性大脑激活和横向化模式.
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