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在患有开角玻璃眼患者的患者中,用于长期维护,Ex-PRESS植入 vs. Trabeculectomy

Kana Tokumo¹, Naoki Okada¹, Hiromitsu Onoe¹

¹Department of Ophthalmology and Visual Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.

Clinical ophthalmology (Auckland, N.Z.)

|September 4, 2023

概括

使用米托米C的Ex-PRESS植入 (EXP) 和带切除术 (TLE) 在降低开角玻璃眼患者的眼内压力 (IOP) 中表现出类似的疗效. 手术前使用药物预测了TLE失败,而不是EXP失败.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
外科手术的结果

背景情况:

开角玻璃眼需要有效的手术干预来控制眼内压力 (IOP).
带有线粒素C (TLE) 的带切除术是一种常见的青光眼手术.
快速植入 (EXP) 提供了一个替代性的手术方法.

研究的目的:

为了比较Ex-PRESS植入 (EXP) 与带有mitomycin C的轨道切除术 (TLE) 的疗效.
评估在开角青光眼患者中维持低目标眼内压 (IOP) 的情况.

主要方法:

在73名开角青光眼患者中随机比较EXP和TLE.
在手术后3个月,通过三个目标IOP范围 (≤18,≤15,≤12 mmHg) 定义的手术成功.
分析了早期,中度和晚期青光眼严重程度小组的成功率.

主要成果:

在EXP和TLE组之间在3年内IOP减少没有显著差异.
三年后的成功率相似:A) 60.0% (EXP) 与60.2% (TLE),B) 45.7%与58.1%,C) 31.5%与40.5%.
更高的手术前玻璃眼药物使用与TLE失败相关,但不是EXP失败.

结论:

无论是EXP还是TLE,在开角眼中都实现了类似的低目标IOP和成功率.
手术前的药物负担是TLE失败的重要风险因素.
对于那些药物需求较高的患者来说,EXP可能会带来优势.

关键词:

通过过手术进行过手术.玻璃眼 glaucoma 玻璃眼玻璃眼玻璃眼玻璃眼随机对照临床试验是随机对照临床试验.视野视野视野视野视野

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