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慢性疼痛器械试验中的假控制 - - 在实践中很棘手 - - 一篇评论文章

Selina Johnson1,2, Andreas Goebel1,2

  • 1Walton Centre NHS Foundation Trust, Fazakerley, Liverpool, L9 7BB, UK.

Contemporary clinical trials communications
|September 4, 2023
PubMed
概括

关于非药物治疗慢性疼痛的高质量研究需要仔细考虑假控制. 本综述综合了数据,以指导在疼痛管理中模拟控制器械试验的设计和进行.

关键词:
慢性疼痛是一种慢性疼痛.行为规则 行为规则检查设备 检查设备审查 审查 审查 审查假冒控制 假冒控制方法 方法 方法 方法.

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Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...