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Updated: Jul 17, 2025

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通过纳米孔序列测序对人类白细胞抗原转录异型的基因特异量化

Andrew E O Hughes1, Maureen C Montgomery2, Chang Liu1

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.

Frontiers in immunology
|September 4, 2023
PubMed
概括

长读测序准确量化人类白细胞抗原 (HLA) 转录异型. 虽然拼接变异很少见,但一些HLA-C和HLA-DQB1等位基因表现出独特的拼接模式,扩大了我们对HLA多样性的理解.

关键词:
一个等位基因的特定表达.人类白细胞抗原 (HLA)长时间阅读序列排序.纳米孔测序的测序转录异型的异形.

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