laparoscopic vs. 开放性上腺切除术:在70只患有上腺瘤的狗中进行了术后数据和生存分析
Kirsten L van Bokhorst1,2, Sara Galac1, Hans S Kooistra1
1Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Frontiers in veterinary science
|September 4, 2023
概括
狗的腹腔镜上腺切除术 (LA) 的结果与开放式上腺切除术 (OA) 相似,住院时间更短,并发症更少. 对于上腺瘤和偶发性瘤,建议采用这种不太侵入的方法.
科学领域:
- 兽医外科 兽医外科 兽医外科
- 狗内分泌学 狗内分泌学
- 手术瘤学手术瘤学
背景情况:
- 上腺切除术是对狗的功能上腺瘤和恶性上腺瘤的主要治疗方法.
- 腹腔镜上腺切除术 (LA) 越来越受欢迎,但大规模的临床数据有限.
- 这项研究评估了犬群中LA和开放上腺切除术 (OA) 后的术后结果,复发率和存活率.
研究的目的:
- 为了比较腹腔镜上腺切除术 (LA) 与狗的开放性上腺切除术 (OA) 的疗效和安全性.
- 确定影响上腺切除术后复发和生存的预后因素.
- 根据临床结果,确定LA作为首选的外科手术技术.
主要方法:
- 在2008年至2022年期间接受LA或OA的70只狗的回顾性分析.
- 诊断包括高皮质醇症,花色细胞瘤和上腺意外瘤.
- 收集的数据包括手术持续时间,术后并发症 (高血压,低血压),存活到出院,住院,复发率,无病期和存活时间.
主要成果:
- 在LA和OA之间手术持续时间没有显著差异.
- 与OA (2.2天) 相比,LA组的平均住院时间 (1.5天) 显著较短.
- 在LA和OA组之间,存活到出院的时间,复发率,无病期和存活时间是可比的. 这两种技术的疾病特异性1年,2年和3年生存率都很高 (95%,89%,89%的LA对比92%,88%,81%的OA).
- 瘤大小与复发有显著的关联,并对无病期和生存时间产生了负面影响.
结论:
- 在患有上腺瘤的狗中,LA和OA都表现出有利的结果.
- 拉动手术提供了较短的住院时间和较低的术后并发症率的优势.
- 较少的侵入性腹腔镜方法被认为是选择病例的首选技术,因为长期结果与OA相似.
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