用塔潘塔多尔ER或氧化CR治疗的患者之间的现实世界结果的比较
Mike Durkin1, Jacqueline Pesa2, Jessica Lopatto3
1Janssen Scientific Affairs, LLC, Titusville, New Jersey, USA.
Journal of health economics and outcomes research
|September 4, 2023
概括
塔达尔延长释放 (ER) 和氧化控制释放 (CR) 是治疗慢性疼痛的阿片类药物. 与氧化CR相比,TAPENTADOL ER的使用与较低的医疗保健利用率和成本有关.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 疼痛管理 疼痛管理
背景情况:
- 慢性疼痛管理通常涉及阿片类药物治疗.
- 对比不同阿片类药物配方的经济和利用结果对于医疗保健决策至关重要.
研究的目的:
- 为了比较医疗保健利用率和慢性疼痛患者的匹配队列之间的成本,这些患者接受了TAPENTADOL延长释放 (ER) 与OXYCODONE控制释放 (CR) 治疗.
主要方法:
- 来自Optum研究数据库的追溯索赔数据分析.
- 连续招募和阿片类药物治疗的成人患者的倾向性得分匹配.
- 在6个月的索引后期内比较住院,急诊室访问和医疗保健费用.
主要成果:
- 与氧化CR相比,Tapentadol ER队列的住院率 (14.6%与20.5%) 和急诊室访问率 (33.4%与37.5%) 显著降低.
- 平均总医疗费用较低的TAPENTADOLER (16,510美元),而不是氧化CR (19,330美元).
- 虽然Tapentadol ER的药房费用较高,但住院费用明显较低.
结论:
- 与氧化CR相比,Tapentadol ER与减少医疗保健利用,特别是较少的住院患者和急诊室访问有关.
- 对于用塔达尔ER治疗的患者而言,整体医疗费用明显低于用氧化CR治疗的患者.
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