如何计算动物和人类研究中的样本大小
Xinlian Zhang1, Phillipp Hartmann2,3
1Division of Biostatistics and Bioinformatics, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, United States.
Frontiers in medicine
|September 4, 2023
概括
计算正确的样本大小对于动物和人类研究至关重要. 本综述阐明了关键的统计术语,并提供了实用方法来确定样本大小,这对于强大的研究设计至关重要.
科学领域:
- 生物统计学 生物统计学
- 研究方法研究方法研究方法学
背景情况:
- 准确的样本大小计算对于动物和人类研究的统计有效性至关重要.
- 了解核心统计概念对于适当的样本大小确定至关重要.
研究的目的:
- 定义与样本大小确定相关的关键术语.
- 为在各种研究情景中计算样本大小提供实际指导和示例.
主要方法:
- 审查和定义中央统计术语 (例如,平均值,标准偏差,假设测试,错误,功率,效果大小).
- 对动物和人类研究的样本大小计算的说明性示例.
- 讨论基于先前数据或效应大小大小的样本大小估计方法.
主要成果:
- 澄清样本大小决定的基本统计概念.
- 展示适用于不同研究环境的实用样本大小计算方法.
- 在先前研究数据有限的情况下,关于估计样本大小的指导.
结论:
- 适当的样本大小计算是动物和人类研究中严格研究设计的关键组成部分.
- 本综述为研究人员提供了必要的定义和实践方法,以准确确定样本大小.
- 有效的样本规模规划提高了研究结果的统计能力和可靠性.
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