Pleural mesothelioma Pleural mesothelioma Pleural mesothelioma Pleural mesothelioma Pleural mesothelioma Pleural
Ibiayi Dagogo-Jack1, Beow Y Yeap1, Mari Mino-Kenudson2
1Massachusetts General Hospital Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
JTO clinical and research reports
|September 4, 2023
概括
胸外转移是多发性间皮瘤中常见的,在44%的患者中发生. 建议在胸部以外进行常规成像,因为其患病率很高,并对生存的影响很大.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 胸部外科手术 胸部外科手术
背景情况:
- 目前的指导方针建议进行胸部CT扫描,以评估胸膜间皮瘤的分期和治疗反应.
- 在这些患者中,对于遥远的胸外部位进行连续成像的必要性缺乏共识.
研究的目的:
- 确定被诊断患有多叶膜间皮瘤的患者胸外转移的患病率.
- 调查胸外转移对整体存活时间的影响.
主要方法:
- 在1999年至2022年期间接受治疗的148名胸腔间皮瘤患者的回顾性评估.
- 分析额外胸部成像报告,以确定转移的地点和时间.
- 在表皮质和非表皮质半球瘤之间比较存活率和转移率.
主要成果:
- 44%的患者发展出胸外转移,中位时间为11.5个月.
- 常见的部位包括胸外节点 (22%),腹膜 (20%),骨头 (11%) 和肝脏 (11%).
- 胸外转移与总生存时间显著缩短有关 (HR 5.9,p < 0.001).
结论:
- 胸腔半质瘤经常转移到胸外部位.
- 包括胸外部位在内的常规成像是全面的患者管理的必要条件.
- 早期发现胸外传播对于生存结果至关重要.
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