部分随机化研究资金的下一个方向是什么? 关于RCT和替代方案的可行性
Tom Stafford1, Ines Rombach1, Dan Hind1
1The University of Sheffield, Sheffield, England, UK.
Wellcome open research
|September 4, 2023
概括
为了获得部分研究资金,进行随机对照试验 (RCT) 需要仔细考虑结果,样本大小和统计能力. 对于某些研究资助实验,RCT的替代方案可能更实用和更具成本效益.
科学领域:
- 研究资助研究资助
- 实验设计 实验设计
- 卫生经济学 卫生经济学
背景情况:
- 研究资金的部分随机化是一个新兴的研究领域.
- 随机对照试验 (RCT) 是评估干预的常见方法.
- 为了资助研究,RCT的可行性和适当性需要仔细研究.
研究的目的:
- 概述研究资助研究的部分随机化研究的基本考虑.
- 确定RCT可行且适用于资助研究的场景.
- 讨论RCT的替代方案,当它们不切实际或太昂贵时.
主要方法:
- 对部分随机化研究的基本考虑因素的审查.
- 对RCT在研究资助中的可行性情景的分析.
- 讨论资金流程的替代实验设计.
主要成果:
- 风险试验的成本和可行性取决于目标结果,样本可用性和统计能力.
- 由于样本大小和功率要求,RCT可能不那么实用,并且比预期的更昂贵.
- 对RCT的替代方法可能适用于某些研究资助实验.
结论:
- 对于涉及研究资金部分随机化的研究,仔细规划至关重要.
- 选择方法 (RCT与替代方法) 应以具体的研究目标和约束为指导.
- 对部分随机化实验的考虑可能扩展到其他资金流程实验.
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