在炎症性肠病中疲劳的经济负担
Ashwin N Ananthakrishnan1, Raj Desai2, Wan-Ju Lee3
1Division of Gastroenterology, Massachusetts General Hospital and Harvard medical School, Boston, MA, USA.
Crohn's & colitis 360
|September 4, 2023
概括
疲劳显著增加了医疗保健成本和新诊断的炎症性肠病 (IBD) 患者的资源使用. 这影响了整体和IBD特定的医疗费用.
科学领域:
- 胃肠病学 胃肠病学
- 卫生经济学 卫生经济学
- 临床研究 临床研究
背景情况:
- 炎症性肠病 (IBD) 包括克罗恩病和性结肠炎.
- 疲劳是IBD患者常见但尚未研究的症状.
- 关于新诊断的IBD疲劳带来的经济负担的现实数据有限.
研究的目的:
- 评估疲劳对医疗保健资源利用率 (HCRU) 和成本的影响.
- 为了比较HCRU和IBD患者与疲劳和没有疲劳之间的成本.
- 在新诊断的IBD队列中分析这些影响.
主要方法:
- 对医疗/药房索赔数据 (2000-2019年) 的回顾性分析.
- 具有 (病例) 和没有 (对照) 疲劳的IBD患者的倾向性得分匹配.
- 12个月的随访疲劳后诊断,以比较HCRU和成本.
主要成果:
- 匹配的队列包括超过42,000名患者 (42%的克罗恩病,58%的性结肠炎).
- 疲劳病例显示,门诊诊次数 (IRR 1.64) 和住院次数 (IRR 1.92) 显著增加.
- 在疲劳病例中,总的直接医疗保健费用大幅增加 (24,620美元与15,324美元相比).
结论:
- 疲劳与新诊断IBD的医疗保健资源利用率增加有关.
- 疲劳的存在显著提高IBD患者的总医疗费用.
- 这些发现凸显了IBD患者疲劳带来的经济后果.
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