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菌泛眼炎呈现为严重的后硬化症
Lynn W Sun1, Therese M Sassalos2, Amy D Zhang2
1Department of Ophthalmology, Oregon Healthy and Science University, United States.
American journal of ophthalmology case reports
|September 4, 2023
概括
这一案例突出显示了一种罕见的真菌泛眼炎,模仿后背硬化炎的二次角度关闭. 尽管最初的真菌培养结果是负面的,但病理检查证实了酵母,强调了有风险的患者需要高度怀疑.
科学领域:
- 眼科医生 眼科 眼科
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
背景情况:
- 后硬化症是一种罕见的疾病,感染性或真菌病因甚至更为罕见.
- 性硬化症往往呈现异常,模仿其他眼睛病理,如角闭眼镜等.
- 由于负面培养和缺乏临床怀疑,真菌性硬化症的诊断不足可能会发生.
研究的目的:
- 报告一种独特而激烈的传染性真菌泛虫病例.
- 为了说明最初的呈现,作为二次向后缩炎的角度闭合.
- 强调诊断挑战和考虑真菌病因学的重要性.
主要方法:
- 一个57岁的妇女患有糖尿病和自身免疫性疾病的病例报告.
- 临床表现包括单侧平坦的前腔,高眼内压和化学反应.
- 诊断工作包括超声波B扫描,血液检查和广泛的感染性工作,包括真菌培养物.
- 治疗包括抗生素,NSAIDs和高剂量的皮质类固醇.
- 进行了眼球核切除和病理检查.
主要成果:
- 患者呈现出暗示后硬化和角关闭的症状.
- 最初的感染性工作,包括真菌培养,是负面的.
- 尽管接受了治疗,但该患者出现了角膜缩失补偿和球球穿孔.
- 对无核眼的病理检查揭示了玻璃体中芽酵母的密集焦点.
结论:
- 性硬化症可以潜伏地呈现,并模仿其他严重的眼部疾病.
- 负真菌培养物不应排除考虑真菌病因,特别是高风险患者.
- 早期怀疑和适当的诊断采样 (水性/玻璃性水龙头) 对于及时诊断和治疗真菌眼部感染至关重要.
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