以形态测量为基础的放射学,用于预测放射治疗后质瘤患者的治疗反应
Lahanda Purage G Sherminie1, Mohan L Jayatilake1, Badra Hewavithana2
1Department of Radiography/Radiotherapy, Faculty of Allied Health Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
Frontiers in oncology
|September 4, 2023
概括
放射学可以预测质瘤治疗反应. 基于形态学的放射学特征在放射治疗后预测质瘤患者治疗反应时达到86%的准确性.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 质瘤在瘤管理中带来了重大挑战.
- 评估治疗反应对于指导患者治疗策略至关重要.
- 放射学为预测治疗结果提供了一个有前途的方法.
研究的目的:
- 调查基于形态学的放射学特征在预测放射治疗中的质瘤患者治疗反应中的有用性.
主要方法:
- 从105张磁共振 (MR) 图像中提取了形态特征,以开发放射学特征.
- 开发和评估机器学习模型来预测治疗反应,有或没有特征选择.
- 使用精度和曲线下的面积 (AUC) 评估模型性能.
主要成果:
- 瘤等级是放射学特征中最重要的贡献者.
- 随机森林算法为预测模型带来了最高的准确性.
- 该模型在没有特征消除的情况下实现了86%的准确性和0.91 AUC,在特征消除的情况下实现了84%的准确性和0.92 AUC.
结论:
- 基于形态学的放射学特征可以作为一种非侵入性生物标志物,用于预测放射治疗后质瘤患者的治疗反应.
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