出口成本对瓦伦尼克林利用和持久性的影响
Aaron Galaznik1, Katherine Cappell2, Leslie Montejano2
1Pfizer Inc., New York, NY, USA.
Journal of health economics and outcomes research
|September 4, 2023
概括
戒烟药物瓦雷尼克林的更高的自费成本与患者使用量和持续性减少有关. 这凸显了成本对戒烟计划的治疗坚持的影响.
科学领域:
- 卫生经济学和研究成果研究成果
- 药物经济学 药物经济学
- 公共卫生 公共卫生
背景情况:
- 瓦伦尼克林是一种处方药,用于戒烟.
- 患者自付的费用可能会影响药物服药和治疗成功.
- 了解与成本相关的障碍对于优化戒烟干预至关重要.
研究的目的:
- 分析瓦伦尼克林的患者自付费用与其利用之间的关联.
- 评估瓦雷尼克林自付费用对治疗持续性的影响.
- 评估不同保险覆盖限制如何影响瓦雷尼克林的获取和遵守.
主要方法:
- 来自MarketScan®商业索赔和遭遇数据库 (2009) 的非识别索赔数据的回顾性分析.
- 包括18岁以上的持续入学患者,按保险计划限制和自付费用 (<12美元,12美元-24.99美元,≥25美元) 分类.
- 药物使用量以药物声明的存在来定义;持久性以数天的供应和停止时间来衡量,使用通用线性模型和时间到事件分析进行分析.
主要成果:
- 更高的自费成本与瓦雷尼克林启动的可能性显著降低相关,特别是在事先授权或戒烟计划要求下.
- 在无限制访问组中,高自费费用的患者与低费用的患者相比,完成瓦雷尼克林治疗的可能性一半.
- 有趣的是,在戒烟计划要求的队列中,更高的自费成本显示了增加完成的趋势,尽管在所有比较中都没有统计学意义.
结论:
- 瓦雷尼克林的高额自付费用通常会降低患者的使用率和治疗持续性.
- 这些发现强调了成本在戒烟的药物获取和服药方面的关键作用.
- 政策影响表明,减少患者的成本共享可能会提高卫生计划和雇主的戒烟计划的有效性.
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