基于高血压的慢性疾病模型在初级保健机构
Eduardo Thadeu de Oliveira Correia1,2, Jeffrey I Mechanick3, Antonio José Lagoeiro Jorge2
1Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
International journal of cardiology. Cardiovascular risk and prevention
|September 4, 2023
概括
基于高血压的慢性疾病 (HBCD) 的新型模型有效地对心脏代谢风险进行了分类. 较高的HBCD阶段与较差的健康结果相关,包括增加的死亡率和心血管事件.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
背景情况:
- 心脏代谢风险是一个重大的公共卫生挑战.
- 现有的基于驱动器的慢性疾病模型缺乏关于新型高血压基础慢性疾病 (HBCD) 模型的数据.
- 这项研究解决了对HBCD模型患病率,特征和预后意义的数据需求.
研究的目的:
- 调查基于高血压的慢性疾病 (HBCD) 模型的患病率和特征.
- 在初级保健队列中评估HBCD阶段的预后意义.
- 验证HBCD模型作为理解心脏代谢风险进展的工具.
主要方法:
- 在巴西,随机选择了633名初级保健参与者 (年龄≥45岁) 的队列.
- 参与者接受了心电图和组织多普勒回声心电图.
- 参与者被分为HBCD阶段 (1-4) 并按照预后分析进行中位数6年的随访.
主要成果:
- 患病率:1.3%没有风险因素,10.0%第一阶段,14.7%第二阶段,51.5%第三阶段,22.5%第四阶段
- 恶化的HBCD阶段与较差的功能,不良的心声学标志物,较高的BMI和增加的2型糖尿病患病率相关.
- 所有原因的死亡率或心血管住院率在HBCD阶段 (阶段1:3.6%至阶段4:39.5%) 显著增加.
结论:
- 基于高血压的慢性疾病 (HBCD) 模型在概念上和预后上都是有效的.
- HBCD阶段与恶化心脏和脏健康标志物有显著的关联.
- HBCD模型预测死亡率和心血管住院的风险增加.
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