瓶子中的心痛:了解酒精性心肌病变性
Nkechinyere L Ihekire1, Okelue E Okobi2,3, Enoobong Aderonke Adedoye4
1Internal Medicine, Windsor University School of Medicine, Cayon, KNA.
Cureus
|September 4, 2023
概括
酒精性心肌病 (ACM) 的风险在每日饮酒量超过80g至少五年时显著增加. 这种情况涉及有害的心肌变化,禁欲是主要治疗方法.
科学领域:
- 心脏病学 心脏病学
- 毒理学 毒理学 毒理学
- 内部医学 内部医学
背景情况:
- 酒精性心肌病变 (ACM) 是一种与滥用酒精有关的心脏病.
- 导致ACM的精确门和酒精消费的持续时间尚未完全理解.
- 了解ACM最近的进展是非常重要的,因为正在进行的滥用酒精.
研究的目的:
- 系统地审查有关酒精性心肌病的当前知识.
- 确定最近的发现是否改变了对ACM的理解.
- 评估酒精滥用与心脏功能障碍之间的关系.
主要方法:
- 在PubMed.com上进行了系统的文献搜索.
- 纳入标准集中在ACM,酒精滥用和人类/动物模型中的心脏功能障碍 (过去10年,英语).
- 包括18篇文章;使用Cochrane工具评估偏差风险.
主要成果:
- 至少五年内每天摄入超过80克的酒精显著增加了ACM的可能性.
- ACM与细胞,结构和组织学心肌损伤有关.
- 诊断通常涉及排除重饮者心脏功能障碍的其他原因.
结论:
- 戒酒是ACM治疗的基石.
- 管理二次性心力衰竭和相关并发症是必不可少的.
- 可能需要进一步的研究来确定ACM的确切的临床和组织学特征.
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