将动物园动物癌症置于正确的视角
Marcus Clauss1, Dennis W H Müller2
1Clinic for Zoo Animals, Exotic Pets and Wildlife, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Zoo biology
|September 4, 2023
概括
癌症主要是老年人的疾病. 动物园动物对癌症易感性的研究必须考虑物种.
科学领域:
- 比较性瘤学研究
- 动物园生物学动物园生物学
- 动物的长寿 动物的长寿
背景情况:
- 动物园动物的癌症研究正在引起人们的注意,以深入了解人类寿命延长和癌症.
- 1933年确立的一个关键原则是,癌症主要是与年龄相关的疾病.
- 这一原则强调了在癌症研究中需要考虑动物园种群的"相对年龄".
研究的目的:
- 重新强调年龄作为动物学环境中的比较癌症研究的关键因素的重要性.
- 倡导对动物园动物癌症患病率的细微了解,将其与特定物种的寿命和养殖联系起来.
主要方法:
- 动物园种群的"相对年龄"被定义为达到的平均寿命,作为最大物种寿命的百分比.
- 将这个指标应用于各种动物园种类的现有和最近的癌症流行数据.
- 分析了相对年龄和癌症患病率之间的相关性,特别是在食肉动物中.
主要成果:
- 与最大寿命相比,平均寿命更长的物种表现出更高的癌症患病率.
- 特别是食肉动物,在动物园中达到相对较长的年龄时,癌症患病率更高的显着趋势.
- 改善的畜牧业,导致更长的寿命,预计将增加癌症发病率作为自然后果.
结论:
- 动物园动物的癌症可以作为有效畜牧业和改善寿命的指标.
- 动物园应该主动管理与年龄相关的疾病,包括癌症,作为成功长期护理的副产品的期望.
- 建议从传感性疾病转变为接受它作为成功衰老和养殖的标志.
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