子 (Oryctolagus cuniculus) 增加了白内障的吸收,增加了饮食中的水平
Annette Liesegang1, Bettina Burger2, Thérèse de Vries de Heekelingen3
1Institute of Animal Nutrition and Dietetics, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Journal of animal physiology and animal nutrition
|September 4, 2023
概括
草食甚至在高食水平下也能积极吸收更多的 (Ca),这挑战了关于被动吸收的假设. 这种活性的吸收,特别是在白肠中,表明有故意的机制可能支持后肠微生物的健康.
科学领域:
- 比较生理学比较生理学
- 胃肠道生物学 胃肠道生物学
- 营养物质的吸收营养物质的吸收.
背景情况:
- 后肠发酵的食草动物往往吸收的 (Ca) 超过所需,通过尿液排泄剩余的.
- 这种过剩的Ca吸收的原因,可能是为了帮助后肠微生物的可用性,仍然不清楚.
研究的目的:
- 研究子 (Oryctolagus cuniculus) 活跃吸收的机制和饮食影响.
- 为了测试草食动物故意管理Ca吸收,以使其肠道微生物组受益的假设.
主要方法:
- 用四种不同的饮食养的子进行了使用室实验.
- 在不同肠道部分测量了活性的吸收.
- 量化了calbindin-D9K (CB) 和维生素D受体 (VDR) 蛋白质的表达.
主要成果:
- 子通过更高的食卡路里水平增加了活性卡路里吸收,这与被动吸收占主导地位的预期相反.
- 在盲肠中,Ca的吸收明显高于十二指肠.
- 饮食中增加的Ca与较高的CB和VDR水平相关,但它们的分布表明其他调节因素.
结论:
- 子的Ca吸收是积极调节,即使在高的饮食水平,支持故意去除假设.
- 高囊吸收率对于哺乳动物来说是不寻常的,需要进一步研究.
- 其他尚未研究的因素显著影响子的Ca吸收,突出显示了草食动物消化过程中的复杂相互作用.
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