防晒可以在红细胞紫外线暴露后保护人体皮肤微生物群
Rolf Schuetz1, Joshua Claypool2, Riccardo Sfriso1
1Personal Care and Aroma, DSM Nutritional Products Ltd, Kaiseraugst, Switzerland.
International journal of cosmetic science
|September 4, 2023
概括
防晒可以保护皮肤微生物群免受紫外线损伤,促进有益的细菌,如乳酸菌,并减少有害的菌. 这表明了皮肤健康的新光保护策略.
科学领域:
- 皮肤病学和微生物学
- 皮肤微生物组研究研究
- 光保护研究研究 光保护研究
背景情况:
- 紫外线辐射 (UVR) 是导致皮肤过早衰老的主要原因.
- 关于紫外线对皮肤微生物群的影响的数据有限.
- 了解紫外线与皮肤微生物群的相互作用对于开发有效的护肤至关重要.
研究的目的:
- 为了研究红色体紫外线暴露对皮肤微生物群的影响.
- 评估紫外线过器对紫外线诱导的微生物组变化的保护能力.
- 探索防晒应用引起的潜在有益的微生物变化.
主要方法:
- 在体内试点研究10名女性志愿者使用SPF20防晒和安慰剂.
- 红斑剂量 (2 MED) 紫外线照射应用于治疗和未治疗的皮肤区域.
- 通过16S rRNA Amplicon和Shotgun元基因组测序进行皮肤微生物组分析.
- 在体外测试紫外线过器对细菌生存的影响.
主要成果:
- 皮肤微生物群的多样性显示出显著的个体间差异和治疗效应.
- 杆菌是丰富的,并影响了多样性.
- 与紫外线或安慰剂不同的是,乳酸菌的丰富度在防晒剂治疗时增加.
- 防晒促进了一个有益的微生物网络,以微型菌属为中心.
- 紫外线过器对关键细菌物种的生存产生了特殊影响.
结论:
- 防晒剂SPF20治疗对皮肤微生物组进行了积极调节.
- 防晒保护的乳酸菌克里斯帕图斯和减少的.
- 紫外线过器可以通过影响特定的微生物群体提供有针对性的光保护.
- 这些发现支持基于微生物组调节的UV保护新型化品策略的开发.
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