如何在左心房附属体内突出轨道是影响心房的患者血栓形成的关键因素
Juanzhang Liu1, Taihui Yu2, Chaodi Tan1
1Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
The international journal of cardiovascular imaging
|September 4, 2023
概括
在左心房附属体 (LAA) 中的凸角 (TPA) 与非膜性心房动患者的血栓形成风险显著相关. 增加的TPA独立地预测LAA血栓和污泥形成,提供了一个新的风险评估工具.
科学领域:
- 心血管医学 心血管医学
- 医疗成像医学成像
- 血栓形成研究研究
背景情况:
- 左心房附属体 (LAA) 是非膜心房动患者中血栓形成的主要部位.
- 在LAA内肌肉心脏轨道突起与血栓形成的发生之间的关系以前没有被确立.
研究的目的:
- 为了研究LAA中状骨突起的程度与LAA血栓或污泥的存在之间的关联.
- 评估状骨突出的角度 (TPA) 作为潜在的LAA血栓形成的独立风险因素.
主要方法:
- 对485名患有非膜性心房的患者进行了回顾性研究,这些患者接受了射频除.
- 根据LAA成像,患者被分为血栓,污泥和正常组.
- 使用CT扫描量化尾突出的角度 (TPA);采集临床数据和LAA排空速度进行比较.
主要成果:
- 与正常组相比,血栓和污泥组的平均TPA显著高于正常组.
- 在增加TPA和LAA血栓和污泥发生率之间观察到正相关性.
- 多变量分析确定TPA是LAA血栓 (OR=1.046) 和污泥 (OR=1.035) 的独立风险因素.
结论:
- 轨道突出的角度 (TPA) 是一个可靠的测量,反映了LAA轨道突出.
- 升高的TPA是一个独立的风险因素,在非膜动患者中发展LAA血栓或污泥.
- 在LAA中,TPA作为潜在的成像生物标志物用于评估未来的血栓形成风险.
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