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单独进行血栓切除术与静脉内血栓溶解前进行血栓切除术,用于急性基底动脉封闭

Meng Guo^1,2, Chengsong Yue², Jie Yang²

¹Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China.

Journal of neurointerventional surgery

|September 4, 2023

概括

对于急性基底动脉阻塞中风,在内血管治疗之前桥接静脉血栓溶解显示出与直接EVT相似的结果. 两种方法之间没有观察到功能结果,出血或死亡率的显著差异.

科学领域:

神经学神经学
干预神经病学干预神经病学
脑卒中医学脑卒中医学

背景情况:

内血管治疗 (EVT) 是急性缺血性中风的标准.
在急性基底动脉封闭 (BAO) 时,在EVT之前弥合静脉内血栓溶解 (IVT) 的益处尚不清楚.
这项研究比较了直接EVT与桥梁IVT,然后在BAO患者中进行EVT.

研究的目的:

为了比较直接EVT的疗效和安全性与EVT之前的桥梁IVT.
评估急性BAO患者的功能结果和安全概况.

主要方法:

来自BASILAR注册表的647名急性BAO患者的多中心队列研究.
患者接受了直接EVT或桥梁IVT,随后接受了EVT.
主要结局:独立的功能结局 (修改的兰金尺度[mRS] 0-2). 二级结局:优秀/有利的功能结局,死亡率,症状性内出血 (sICH),90天后再输血.

主要成果:

在直接EVT和桥梁IVT组 (27.3%对27.7%) 之间,类似的初级结局 (mRS 0-2).
两组之间90天死亡率 (46.8%与43.7%) 或症状性内出血 (7.3%与6.0%) 没有显著差异.
功能性结果分布和再输率是可比的.

结论:

在EVT之前跨越IVT产生了类似的功能结果,以在急性BAO患者中指导EVT.
在这两种治疗策略之间,没有发现症状性内出血或死亡率的显著差异.
直接EVT和桥梁IVT是急性BAO的可比治疗选择.

关键词:

干预干预干预一次性中风,中风.进行血栓切除术 (thrombectomy).血栓溶解是一种血栓溶解.

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