移民和精神分裂症和双相情感障碍的风险:瑞典国家研究
Natassia Robinson1, Alexander Ploner1, Roxana Müller-Eberstein1
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Schizophrenia research
|September 4, 2023
概括
移民身份,移民时的年龄,性别和原产地影响精神分裂症 (SCZ) 和双相情感障碍 (BD) 风险. 儿童移民面临更高的SCZ风险,而BD风险因年龄和出身而异.
科学领域:
- 精神病学是一个精神病学.
- 流行病学 流行病学
- 社会学 社会学 社会学
背景情况:
- 精神分裂症 (SCZ) 的风险在移民中较高,但双相情感障碍 (BD) 的风险和影响因素仍未得到充分研究.
- 移民特征如移民时的年龄,原籍地区和性别可能会影响SCZ和BD风险.
研究的目的:
- 与本地出生的人口相比,研究第一代和第二代移民中的SCZ和BD风险.
- 分析移民时的年龄,原籍地区,性别和父母的移民身份如何改变SCZ和BD风险.
主要方法:
- 一个嵌套的病例控制研究利用了5539个SCZ和20577个BD病例 (1988-2013),与基于人口的对照进行了匹配.
- 条件后勤回归分析了根据移民身份,地区和移民时的年龄分类的风险,按性别分层.
主要成果:
- 第一代移民的SCZ增加,BD风险降低.
- 童年移民与更高的SCZ风险相关 (特别是来自非洲),而BD风险随着移民年龄的增长而下降.
- 第二代移民和男性的SCZ和BD诊断增加,风险因父母的移民身份而异.
结论:
- 移民时的年龄,性别和原产地是影响SCZ和BD风险的重要因素.
- 需要进一步的研究来了解与迁移相关的病因和这些疾病的诊断模式.
相关概念视频
Psychological and Sociocultural Causes of Schizophrenia
125
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
125
Biological Causes of Schizophrenia
93
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
93
Bipolar Disorder
102
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
102
Schizophrenia
130
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
130
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
740
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
740
Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K


