TMPRSS11D/ALR介导的ER压力调节了宫癌微环境中的骨髓原抑制细胞的功能

Sifang Feng1, Juan Zhao2, Ting Yang2

  • 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

PubMed
概括

跨膜血清蛋白酶11D (TMPRSS11D) 通过增强骨髓衍生抑制细胞 (MDSC) 免疫抑制,促进子宫癌免疫逃避. 沉默TMPRSS11D减少瘤生长和MDSC积累,提供了一个潜在的治疗点.

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