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Updated: Jul 17, 2025

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
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Published on: October 4, 2017

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结构洞察为什么S-链糖化不能充分模仿自然O-糖化作用的结构洞察

Chao Chen1, Bo Ma2, Yefei Wang3

  • 1CAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Engineering Laboratory of Single Cell Oil, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao, Shandong 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao, Shandong 266101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

International journal of biological macromolecules
|September 4, 2023
PubMed
概括

从O-糖化转换为S-糖化可能会改变蛋白质的稳定性和结合性. 这项研究揭示了不同的甘氨酸链接如何影响蛋白质功能,建议在甘氨酸工程中谨慎使用.

关键词:
碳水化合物结合模块的使用葡萄糖基酶化是什么? 葡萄糖基酶化分子动态模拟分子动态模拟核磁共振是一种核磁共振.结构 结构 是一个结构.

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