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Colleen Ziegler1, Alain Mir2, Sangeetha Anandakrishnan2

  • 1bioSyntagma, Tempe, Arizona, USA.

Molecular oncology
|September 4, 2023
PubMed
概括

一种新的空间分析方法揭示了乳腺癌中独特的免疫微环境状态,提供了超越当前诊断的见解,例如PD-L1测试用于预测治疗反应.

关键词:
免疫瘤学 免疫瘤学空间配置文件的空间配置文件三重阴性乳腺癌是什么瘤微环境是一个微环境.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...