在免疫接种后出现不良事件的患者中,与重接种意图相关的因素
Caroline E Muñoz1, Anne Pham-Huy2, Jeffrey M Pernica3
1Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada; Canadian Center for Vaccinology, IWK Health, Nova Scotia Health, and Dalhousie University, Halifax, Nova Scotia, Canada.
Vaccine
|September 4, 2023
概括
在推再接种疫苗时,医生考虑不良事件类型和影响,而患者则专注于影响. 这项研究有助于为经历免疫接种后不良事件 (AEFI) 的人提供咨询.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 免疫接种后的不良事件 (AEFI) 可以给患者和医疗保健提供者带来关于再接种疫苗安全性的不确定性.
- 加拿大特殊免疫诊所 (SIC) 网络评估AEFI,并提供有关后续接种疫苗的指导.
研究的目的:
- 确定影响医生在AEFI后对再接种疫苗的建议的因素.
- 确定影响患者在AEFI后重新接种疫苗的意图的因素.
主要方法:
- 在加拿大SIC网络 (2013-2019) 中进行了一项前性观察研究.
- 数据包括AEFI的标准化评估,医生重新接种疫苗的建议和患者的意图.
- 对AEFI影响进行了分类 (低,中等,高,严重),并使用多变量逻辑回归进行分析.
主要成果:
- 医生建议与AEFI类型和影响有关. 立即过敏和新的自身免疫性疾病降低了推可能性.
- 与低影响事件相比,更高的AEFI影响显著降低了医生对再接种疫苗的建议.
- 患者对再接种的意图主要与AEFI影响有关,对高影响AEFI的意图减少.
结论:
- 医生在重新接种疫苗的建议中考虑AEFI类型和影响.
- 患者关于再接种疫苗的决定主要受到AEFI的感知影响的影响.
- 这些发现可以为改善患者在不良事件后重新接种疫苗的咨询提供信息.
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